pronouns: he/him
role: Principal Investigator
A proud Pitzer College alum, Patrick received his Ph.D. from the UW Molecular and Cellular Biology (MCB) Graduate Program at the Fred Hutchinson Cancer Research Center under the mentorship of Harmit Malik and Michael Emerman, where he studied the evolution of host-virus interactions. Patrick nex
pronouns: he/him
role: Principal Investigator
A proud Pitzer College alum, Patrick received his Ph.D. from the UW Molecular and Cellular Biology (MCB) Graduate Program at the Fred Hutchinson Cancer Research Center under the mentorship of Harmit Malik and Michael Emerman, where he studied the evolution of host-virus interactions. Patrick next conducted his postdoctoral training with Russell Vance at the University of California, Berkeley, where he studied the evolution, mechanisms, and functional consequences of innate immune sensors that detect 'pathogen-specific activities.' He's thrilled to be back in Seattle as an Assistant Professor in the Department of Microbiology at UW. When not in the lab, Patrick enjoys cooking and exploring the beauty of the Pacific Northwest. He's also an avid Seattle sports fan.
pronouns: she/her
role: Research Technician
Olivia grew up in Sammamish Washington, and recently completed her B.S. in Molecular and Cell Biology at Western Washington University. While pursuing her undergrad, she tried out a few different research fields before finding the one that clicked. Her research journey originally started in a Mari
pronouns: she/her
role: Research Technician
Olivia grew up in Sammamish Washington, and recently completed her B.S. in Molecular and Cell Biology at Western Washington University. While pursuing her undergrad, she tried out a few different research fields before finding the one that clicked. Her research journey originally started in a Marine Mammal Ecology Lab where she got to watch adorable seals swim around the bay. But after a few weeks of sitting out in the rain, she quickly decided that fieldwork wasn’t for her. She eventually found her way to Dr. Dan Pollard’s Genetics Lab where she studied the dynamics of gene expression in S. cerevisiae. While at WWU, Olivia was engaged in many community groups supporting marginalized identities, and holds particular passion for advancing Accessibility, Diversity, Equity, and Inclusion (ADEI) in STEM. As she establishes her career in science, she hopes to both address human health disparities, and help make the field more equitable and inclusive. Looking to learn more about how organisms stay healthy, and needing a break from being a student, she joined the Mitchell Lab and is excited to work closely with Dr. Ryan Tibble to examine inflammasome activation. Outside of research, Olivia enjoys cooking, weightlifting, and can often be found crocheting or knitting with an audiobook or TV show.
pronouns: she/her
role: Research Technician
Shania was born in Dededo, Guam before moving to Puyallup, WA where she spent most of her childhood. She went to the University of Washington and graduated in 2021 with a Bachelor’s of Science in Microbiology. Her research career began her senior year when she joined the Reniere lab as a laborator
pronouns: she/her
role: Research Technician
Shania was born in Dededo, Guam before moving to Puyallup, WA where she spent most of her childhood. She went to the University of Washington and graduated in 2021 with a Bachelor’s of Science in Microbiology. Her research career began her senior year when she joined the Reniere lab as a laboratory assistant and moved up to an undergraduate researcher position. During her time as an undergraduate researcher she was under the tutelage of graduate student Monica Cesinger. The two sought to learn more about the role of the transcriptional regulator spxA1 in Listeria monocytogenes in terms of determining cell shape. This was done by creating a GFP-FtsZ protein that would be put into L.monocytogenes and be used to observe the irregular septum ring formation that’s characteristic of ΔspxA1 bugs. Shortly after graduation, Shania was employed to be a full-time research scientist assistant and lab manager for the Reniere lab. Outside of the lab, she enjoys cooking/baking, drawing, going to farmers markets, and spending time with her rabbit, Oreo.
pronouns: he/him
role: Research Technician II
Born and raised on Guam, Zach is a proud CHamoru/Filipino who moved to Seattle and joined the Mitchell Lab to gain more experience in infectious disease research. He received his Bachelors of Science in Biology at the University of Guam and discovered his interest in research after interning at
pronouns: he/him
role: Research Technician II
Born and raised on Guam, Zach is a proud CHamoru/Filipino who moved to Seattle and joined the Mitchell Lab to gain more experience in infectious disease research. He received his Bachelors of Science in Biology at the University of Guam and discovered his interest in research after interning at various labs. This includes his time under the mentorship of Dr. Floyd Reed, where he helped investigate methods of genetic pest management for invasive Aedes albopictus and Culex quinquefasciatus mosquitoes from spreading vector-borne diseases in human and wildlife populations in Hawai’i. After graduation, he was a field technician for several local and federal agencies researching methods of eradication for invasive Brown Treesnakes (Boiga irregularis) on Guam, where many of its native species of plants and animals have become threatened or extinct due to the introduction of various invasive species. He is excited to apply his experience working with animals to help Dr. Stef Krug with managing the laboratory mouse colony and assisting with her research. Outside of work, you can find Zach binging TV shows, exploring the outdoors, or cooking up his favorite foods.
After growing up in Germany, Stef moved to Massachusetts where she received her Associate’s degree in Liberal Arts from Greenfield Community College and her Bachelor’s with departmental honors in Biology from UMass Amherst. As an undergraduate researcher and lab technician, she investigated T. pallidum protein-protein interactions (Dr. Pe
After growing up in Germany, Stef moved to Massachusetts where she received her Associate’s degree in Liberal Arts from Greenfield Community College and her Bachelor’s with departmental honors in Biology from UMass Amherst. As an undergraduate researcher and lab technician, she investigated T. pallidum protein-protein interactions (Dr. Peter Uetz); T. brucei kDNA replication (Dr. Michele Klingbeil); circadian rhythms (Dr. Eric Bittman); sexually divergent neuronal cell death (Dr. Nancy Forger); and HPT axis development (Dr. Ksenia Tonyushkina) before pursuing her Ph.D. in Cellular and Molecular Medicine (CMM) at the Johns Hopkins SOM under the mentorship of Dr. Bill Bishai. Her doctoral work identified the master regulator PARP1 as a host target of the antibiotic pyrazinamide and as a molecular determinant of sex differences in tuberculosis. Other projects focused on elucidating the roles of MDSCs, RIPK1, MDA5, and the integrated stress response in tuberculosis host-pathogen interactions. As a postdoc in the Mitchell lab, she is excited to study inflammasome activation as a mechanism of pathogen sensing. In her free time, Stef is a volunteer ski patroller and an avid disc golfer and mountain biker.
Jessie is from the San Francisco Bay Area in sunny California. She earned her B.S in Pharmacology from the University of California, Santa Barbara where she had her first research experience in Denise Montell’s lab studying the role of stress granules in anastasis, a form of cell recovery. After graduating, she returned to San Francisco t
Jessie is from the San Francisco Bay Area in sunny California. She earned her B.S in Pharmacology from the University of California, Santa Barbara where she had her first research experience in Denise Montell’s lab studying the role of stress granules in anastasis, a form of cell recovery. After graduating, she returned to San Francisco to work in the lab of Andreas Puschnik at the Chan Zuckerberg Biohub where she conducted genome-wide CRISPR screens to identify and characterize cellular host factors important for viral infection. Excited to further explore her passion for virology, Jessie bought a raincoat and moved to Seattle to pursue her Ph.D in the UW Molecular and Cellular Biology (MCB) Graduate Program at the Fred Hutchinson Cancer Center under the co-mentorship of Patrick Mitchell and Michael Emerman (yes, the same one that mentored Patrick!). . Jessie earned her Ph.D. in 2024.
Outside the lab, Jessie enjoys biking, playing her ukulele, crocheting cute critters, and hanging out with her cat CRISPR Cats9
Ryan hails from Port Huron, a town in Michigan’s ‘thumb’. He earned a BA and MS from Dartmouth College where he spent four years in the lab of F. Jon Kull studying the structure and function of unique kinesin-like proteins. Ryan then headed west to the University of California - San Francisco and received his PhD with John Gross. There, h
Ryan hails from Port Huron, a town in Michigan’s ‘thumb’. He earned a BA and MS from Dartmouth College where he spent four years in the lab of F. Jon Kull studying the structure and function of unique kinesin-like proteins. Ryan then headed west to the University of California - San Francisco and received his PhD with John Gross. There, he examined the regulation of decapping, a critical step in mRNA degradation, by disordered regions and phase separation. In the Mitchell lab, Ryan is excited to characterize new mechanisms of inflammasome activation and how they integrate various danger signals. When he’s not in lab, Ryan can be found outside hiking and biking or trying some new recipes in the kitchen.
Miles grew up in Southern California where he received a B.S. in Microbiology from the University of California, San Diego. While completing his degree, he had the privilege of working under Dr. Matthew Daugherty, where he investigated host-viral arms races involving innate antiviral proteins and viral proteases. With a fascination for vi
Miles grew up in Southern California where he received a B.S. in Microbiology from the University of California, San Diego. While completing his degree, he had the privilege of working under Dr. Matthew Daugherty, where he investigated host-viral arms races involving innate antiviral proteins and viral proteases. With a fascination for viruses and the Pacific Northwest (and a fear of finding a real job), Miles decided that pursuing a PhD with the UW Microbiology program was the ideal path forward. Under the guidance of Dr. Patrick Mitchell, he is excited to study the determinants of inflammasome activation and viral pathogenesis. In his spare time, Miles indulges in video games and frequents the climbing gym to participate in Seattle’s greatest pastime.
Christina was born and raised in California, where one can drive for multiple hours in any direction and find themselves still in California. Her interest in fictional pathogens from films and novels inspired her to pursue a B.S in Microbiology from the University of California, Davis. After graduating from UC Davis (literally the day aft
Christina was born and raised in California, where one can drive for multiple hours in any direction and find themselves still in California. Her interest in fictional pathogens from films and novels inspired her to pursue a B.S in Microbiology from the University of California, Davis. After graduating from UC Davis (literally the day after), Christina disappeared across the country to Maryland and spent the summer in the Vaccine Research Center at the NIH in the laboratory of Dr. Barney S. Graham. Her summer research project focused on targeting the conserved stem region of influenza hemagglutinin by displaying “headless” HA trimers on self-assembling nanoparticles. Following her summer internship, she returned as a postbaccalaureate research fellow where she focused on the structural characterization and conformational stabilization of influenza neuraminidase. The culmination of her research experiences motivated Christina to pursue her Ph.D. in the UW Microbiology Graduate Program under the mentorship of Patrick Mitchell (who reminded her that inflammasomes exist). During her free time outside of lab, you can either find her asleep or at the boxing/kickboxing gym.
Marisa was born and raised in the greater Seattle area. While earning her BS in Biology at the University of Washington she had her first research experience in Dr. Billie Swalla’s lab at UW's Friday Harbor Laboratories marine station where she spent a quarter studying the genetics of central nervous system regeneration in marine worms. U
Marisa was born and raised in the greater Seattle area. While earning her BS in Biology at the University of Washington she had her first research experience in Dr. Billie Swalla’s lab at UW's Friday Harbor Laboratories marine station where she spent a quarter studying the genetics of central nervous system regeneration in marine worms. Upon returning to Seattle, she spent the rest of her undergraduate career studying cleft palate pathogenesis in Dr. Kai Yu’s lab at Seattle Children’s. After graduating in 2018, she returned to her love of marine invertebrates and genetics and worked as a research technician at Pacific Northwest Research Institute in the lab of Dr. Michael Metzger where she studied transmissible cancers – cancer cells that have evolved to jump between individuals just like pathogens – in clams and mussels. Finding the rain suits her just fine, Marisa chose to stay in Seattle and pursue a PhD in the UW Molecular and Cellular Biology (MCB) program where she is super excited to learn more about innate immunity and host-pathogen interactions under the mentorship of Dr. Patrick Mitchell. While away from the bench, you can often find her cooking/baking, reading, or at one of Washington’s many beaches, looking for sea slugs.
Odko is from Mongolia but she spent half of her life in Lynnwood, WA. She is currently a freshman at the University of Washington in Seattle intending to major in Biology/Physiology. After her undergraduate studies, she plans to attend medical school to become a physician. Some of her hobbies and interests include; bouldering, hiking, and water coloring.
Ayumu is from Tokyo, Japan, currently studying as an exchange student at the University of Washington. He is a 5th-year student at the University of Tokyo, majoring in medicine. His research interests focus on virology, and over the past two years, he has studied the factors that determine the host range of morbilliviruses. This research
Ayumu is from Tokyo, Japan, currently studying as an exchange student at the University of Washington. He is a 5th-year student at the University of Tokyo, majoring in medicine. His research interests focus on virology, and over the past two years, he has studied the factors that determine the host range of morbilliviruses. This research led to his growing interest in immunology, leading him to join the Mitchell Lab. After completing his undergraduate degree, Ayumu hopes to become a researcher specializing in immunology and virology. In his free time, he enjoys watching soccer games.
Alexis is from Oakland, California and is currently a sophomore at the University of Washington majoring in Biology and minoring in Gender, Women, and Sexuality Studies. After undergrad she hopes to go to medical school and become an OB/GYN in order to better address the racial disparities that are prominent in the sphere of women's healt
Alexis is from Oakland, California and is currently a sophomore at the University of Washington majoring in Biology and minoring in Gender, Women, and Sexuality Studies. After undergrad she hopes to go to medical school and become an OB/GYN in order to better address the racial disparities that are prominent in the sphere of women's health. In her free time, Alexis likes to crochet, read, and watch tons of movies.
Aileen grew up in South Korea and began her academic journey by majoring in biology at college. After relocating to Seattle, she pursued an Associate's degree in biology at Bellevue College before transferring to the University of Washington. Now a junior majoring in biology with a focus on physiology, Aileen aims to further her education
Aileen grew up in South Korea and began her academic journey by majoring in biology at college. After relocating to Seattle, she pursued an Associate's degree in biology at Bellevue College before transferring to the University of Washington. Now a junior majoring in biology with a focus on physiology, Aileen aims to further her education through either a PhD in biology or an MD-PhD program. She enjoys sleeping, going to the gym, or playing badminton in her free time.
Emi grew up in the Puget Sound and is a junior at the University of Washington majoring in microbiology. She is interested in vaccine research and hopes to explore the many different career paths in this field. In her free time Emi enjoys spending time with friends and family, playing video games, and practicing kendo.
Michael Lindberg - lab manager (inaugural Mitchell Lab team member) - 2021
Taran Paul - undergraduate researcher - 2021-22
Amandine Chantharath - visiting student from ENS Lyon - 2022
Joy Lee - undergraduate researcher - 2022
Luka Bedalov - undergraduate researcher - 2021-22
Selena Wong - undergraduate researcher - 2021-22
Ashcon Pashai - undergraduate researcher - 2022-23
Katie MacNary - undergraduate researcher - 2022-23
Megan Littlehale - lab manager 2022-24
Serena Furuta - undergraduate researcher 2022-24
Akshara Polavarapu - undergraduate researcher 2024
We're excited to build a supportive and inclusive research team as part of the Department of Microbiology and the greater Seattle research community. If our research and values pique your interest, we have the following openings:
Undergraduates:
MICROM499. Interested students should email me if they are interested. The minimal time commitment is 9h/week (3 credits) per quarter. Note that we are located on the UW SLU campus (not in the Health Sciences Building on main campus).
MICROM496. Interested students should email me if they are interested. I do not take MICROM496 students in Winter quarter. A general course description can be found HERE and an example syllabus can be found HERE. Strong preference for students who are also doing MICROM499 with us.
Graduate students. Rotations available for 2023-24. I am affiliated with UW Microbiology, Molecular and Cellular Biology, Pathobiology, and Immunology graduate programs.
We are actively recruiting a postdoc to study the mechanisms, consequences, and evolution of effector-triggered immunity. There are several available projects in the lab, and it is expected that postdoctoral scholars bring their own excitement, ideas, and expertise to these projects to advance both central aspects of the Mitchell Lab’s research while building an independent research program or working towards their self-defined goals.
We are always on the lookout for scientists who are excited to bring their enthusiasm and expertise to the team to create something new and awesome. If the above description doesn't sound like a fit, but you're still interested, please don't hesitate to email me about a possible position.